CN Patent

CN107556238A — 一种卡博替尼的合成方法

Assigned to WANLE PHARMACEUTICAL CO Ltd SHENZHEN · Expires 2018-01-09 · 8y expired

What this patent protects

本发明提供一种卡博替尼的合成方法，该方法以1,1‑环丙基二羧酸为起始原料，酰化后与4‑[(6,7‑二甲氧基‑4‑喹啉)氧基]苯胺缩合，再与4‑氟苯胺在多肽缩合剂作用下进一步缩合制得卡博替尼，该方法反应条件温和，仅一步使用氯化试剂，适合工业化生产。

USPTO Abstract

本发明提供一种卡博替尼的合成方法，该方法以1,1‑环丙基二羧酸为起始原料，酰化后与4‑[(6,7‑二甲氧基‑4‑喹啉)氧基]苯胺缩合，再与4‑氟苯胺在多肽缩合剂作用下进一步缩合制得卡博替尼，该方法反应条件温和，仅一步使用氯化试剂，适合工业化生产。

Drugs covered by this patent

Patent Metadata

Patent number
CN107556238A
Jurisdiction
CN
Classification
—
Expires
2018-01-09
Drug substance claim
No
Drug product claim
No
Assignee
WANLE PHARMACEUTICAL CO Ltd SHENZHEN
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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