CN Patent

CN107304186B — 一种奥拉帕尼的精制方法

Assigned to Hangzhou Rongli Pharmaceutical Technology Co ltd · Expires 2021-08-27 · 5y expired

What this patent protects

本发明属于药物提纯技术领域，特别涉及一种奥拉帕尼的精制方法,包括以下步骤：1）将奥拉帕尼粗品加入到二氯甲烷和乙腈的混合溶剂，加热回流、冷却结晶；2）将步骤1）所得结晶加入到二氯甲烷和C 1‑5 脂肪醇的混合溶剂中重结晶；3）蒸馏蒸发二氯甲烷，降温析出固体，过滤，水洗，干燥。本发明方法所得奥拉帕尼具有纯度高的特点。

USPTO Abstract

本发明属于药物提纯技术领域，特别涉及一种奥拉帕尼的精制方法,包括以下步骤：1）将奥拉帕尼粗品加入到二氯甲烷和乙腈的混合溶剂，加热回流、冷却结晶；2）将步骤1）所得结晶加入到二氯甲烷和C 1‑5 脂肪醇的混合溶剂中重结晶；3）蒸馏蒸发二氯甲烷，降温析出固体，过滤，水洗，干燥。本发明方法所得奥拉帕尼具有纯度高的特点。

Drugs covered by this patent

Patent Metadata

Patent number
CN107304186B
Jurisdiction
CN
Classification
—
Expires
2021-08-27
Drug substance claim
No
Drug product claim
No
Assignee
Hangzhou Rongli Pharmaceutical Technology Co ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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