CN107266377A — 一种urat1抑制剂的轴手性对映体的多晶型
Assigned to SHANGHAI JINGXIN BIOLOGICAL MEDICAL CO Ltd · Expires 2017-10-20 · 9y expired
What this patent protects
本发明公开了2‑(5‑溴‑4‑(4‑环丙基萘‑1‑基)‑4H‑1,2,4‑三唑‑3‑基硫基)乙酸的S构型轴手性对映体的多晶型I,其使用CuKα辐射、以2θ角度表示的X射线粉末衍射光谱至少在7.02°±0.2°、11.14°±0.2°、14.10°±0.2°、14.60°±0.2°、15.44°±0.2°、16.98°±0.2°、20.98°±0.2°、21.86°±0.2°和28.02°±0.2°处存在衍射峰。相比无定形形式,多晶型I稳定性好,几乎无引湿性,晶型纯度高,便于药物制造、存储和运输。
USPTO Abstract
本发明公开了2‑(5‑溴‑4‑(4‑环丙基萘‑1‑基)‑4H‑1,2,4‑三唑‑3‑基硫基)乙酸的S构型轴手性对映体的多晶型I,其使用CuKα辐射、以2θ角度表示的X射线粉末衍射光谱至少在7.02°±0.2°、11.14°±0.2°、14.10°±0.2°、14.60°±0.2°、15.44°±0.2°、16.98°±0.2°、20.98°±0.2°、21.86°±0.2°和28.02°±0.2°处存在衍射峰。相比无定形形式,多晶型I稳定性好,几乎无引湿性,晶型纯度高,便于药物制造、存储和运输。
Drugs covered by this patent
- Zurampic (LESINURAD) · Ironwood Pharms Inc
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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