CN106806346B — 一种非索非那定盐酸盐干混悬剂制剂及其制备方法
Assigned to Shanghai Advanced Pharmaceutical Engineering Research Center Ltd · Expires 2020-09-11 · 6y expired
What this patent protects
本发明公开了一种非索非那定盐酸盐干混悬剂制剂及其制备方法。该制剂包括：非索非那定盐酸盐0.8％～4％、填充剂80％～93％、甜味剂0.2％～1.2％、助悬剂0.5％～1％、矫味剂0.2％～2％、遮味剂0.2％～5％、润湿剂0％～0.6％、柠檬酸缓冲盐或磷酸缓冲盐1.5％～10％；上述各组分含量总和为100％，且百分比为质量百分比。所述的非索非那定盐酸盐干混悬剂制剂采用湿法制粒制成。本发明的非索非那定盐酸盐干混悬剂制剂稳定性高、流动性好、易于储存；配制成混悬剂后，吸收迅速，生物利用度高，服用方便，口感良好，稳定性高。
USPTO Abstract
本发明公开了一种非索非那定盐酸盐干混悬剂制剂及其制备方法。该制剂包括：非索非那定盐酸盐0.8％～4％、填充剂80％～93％、甜味剂0.2％～1.2％、助悬剂0.5％～1％、矫味剂0.2％～2％、遮味剂0.2％～5％、润湿剂0％～0.6％、柠檬酸缓冲盐或磷酸缓冲盐1.5％～10％；上述各组分含量总和为100％，且百分比为质量百分比。所述的非索非那定盐酸盐干混悬剂制剂采用湿法制粒制成。本发明的非索非那定盐酸盐干混悬剂制剂稳定性高、流动性好、易于储存；配制成混悬剂后，吸收迅速，生物利用度高，服用方便，口感良好，稳定性高。
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Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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