CN Patent

CN106660965A — 乐伐替尼的对甲苯磺酸盐、其结晶形式及制备方法

Assigned to Jiangsu Hengrui Medicine Co Ltd · Expires 2017-05-10 · 9y expired

What this patent protects

本发明公开了乐伐替尼的对甲苯磺酸盐、其结晶形式及制备方法。具体地，本发明公开了乐伐替尼的对甲苯磺酸盐、其I型结晶及制备方法，所述制备方法包括将任意晶型或无定型的乐伐替尼对甲苯磺酸盐固体在单一的有机溶剂或者他们的混合有机溶剂中结晶得到乐伐替尼对甲苯磺酸盐I型结晶。本发明所得到乐伐替尼对甲苯磺酸盐I型结晶具备良好的晶型稳定性和化学稳定性，并且所用结晶溶剂低毒低残留。

USPTO Abstract

本发明公开了乐伐替尼的对甲苯磺酸盐、其结晶形式及制备方法。具体地，本发明公开了乐伐替尼的对甲苯磺酸盐、其I型结晶及制备方法，所述制备方法包括将任意晶型或无定型的乐伐替尼对甲苯磺酸盐固体在单一的有机溶剂或者他们的混合有机溶剂中结晶得到乐伐替尼对甲苯磺酸盐I型结晶。本发明所得到乐伐替尼对甲苯磺酸盐I型结晶具备良好的晶型稳定性和化学稳定性，并且所用结晶溶剂低毒低残留。

Drugs covered by this patent

Patent Metadata

Patent number
CN106660965A
Jurisdiction
CN
Classification
—
Expires
2017-05-10
Drug substance claim
No
Drug product claim
No
Assignee
Jiangsu Hengrui Medicine Co Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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