CN Patent

CN106478522A — 一种马西替坦杂质标准品的制备方法

Assigned to HEFEI JIUNUO MEDICAL TECHNOLOGY Co Ltd · Expires 2017-03-08 · 9y expired

What this patent protects

本发明公开了一种马西替坦杂质标准品的制备方法，是以5‑(4‑溴苯基)‑4,6‑二氯嘧啶为原料，分别与N‑丙基磺酰胺、乙二醇缩合制得1,2‑二[[N‑[5‑(4‑溴苯基)]‑N'‑丙基磺酰胺‑6‑氧代]嘧啶基]乙基二醚粗品，粗品经精制而得纯品，纯品采用常规的分析手段标定含量。本发明提供的杂质制备方法工艺简捷、制备周期短，经标定的产品含量大于99.0％。本发明提供的马西替坦杂质可作为杂质标准品，应用于马西替坦原料及其制剂杂质的定性、定量研究和检测。

USPTO Abstract

本发明公开了一种马西替坦杂质标准品的制备方法，是以5‑(4‑溴苯基)‑4,6‑二氯嘧啶为原料，分别与N‑丙基磺酰胺、乙二醇缩合制得1,2‑二[[N‑[5‑(4‑溴苯基)]‑N'‑丙基磺酰胺‑6‑氧代]嘧啶基]乙基二醚粗品，粗品经精制而得纯品，纯品采用常规的分析手段标定含量。本发明提供的杂质制备方法工艺简捷、制备周期短，经标定的产品含量大于99.0％。本发明提供的马西替坦杂质可作为杂质标准品，应用于马西替坦原料及其制剂杂质的定性、定量研究和检测。

Drugs covered by this patent

Patent Metadata

Patent number
CN106478522A
Jurisdiction
CN
Classification
—
Expires
2017-03-08
Drug substance claim
No
Drug product claim
No
Assignee
HEFEI JIUNUO MEDICAL TECHNOLOGY Co Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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