CN Patent

CN106478520B — 一种马西替坦杂质标准品的合成方法

Assigned to HEFEI JIUNUO MEDICAL TECHNOLOGY Co Ltd · Expires 2018-09-11 · 8y expired

What this patent protects

本发明公开了一种马西替坦杂质标准品的合成方法，是以马西替坦为原料，经无机碱水解制得粗品，粗品经精制而得5‑(4‑溴苯基)‑6‑[2‑[(5‑溴嘧啶基)‑2‑氧基]乙氧基]‑4‑氨基嘧啶纯品。本发明提供的杂质合成方法原料廉价易得、工艺简捷、制备周期短，经标定产品含量大于99.0％。本发明提供的马西替坦杂质可作为杂质标准品，应用于马西替坦原料及其制剂杂质的定性、定量研究和检测。

USPTO Abstract

本发明公开了一种马西替坦杂质标准品的合成方法，是以马西替坦为原料，经无机碱水解制得粗品，粗品经精制而得5‑(4‑溴苯基)‑6‑[2‑[(5‑溴嘧啶基)‑2‑氧基]乙氧基]‑4‑氨基嘧啶纯品。本发明提供的杂质合成方法原料廉价易得、工艺简捷、制备周期短，经标定产品含量大于99.0％。本发明提供的马西替坦杂质可作为杂质标准品，应用于马西替坦原料及其制剂杂质的定性、定量研究和检测。

Drugs covered by this patent

Patent Metadata

Patent number
CN106478520B
Jurisdiction
CN
Classification
—
Expires
2018-09-11
Drug substance claim
No
Drug product claim
No
Assignee
HEFEI JIUNUO MEDICAL TECHNOLOGY Co Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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