CN Patent

CN106432231B — Azd9291的药用盐、及其晶型和制备方法

Assigned to Wuxi Baiaode Biological Science Co.,Ltd. · Expires 2018-06-12 · 8y expired

What this patent protects

本发明公开了新的AZD9291药用盐，所述AZD9291的化学结构式如下：，所述药用盐为硫酸盐、对甲苯磺酸盐、酒石酸盐、醋酸盐或柠檬酸盐。本发明所提供的AZD9291药用盐具有与AZD9291甲磺酸盐相当或更高的溶解度，能满足生物利用度和药效要求，而且生物安全性更高，引湿性更低，克服了现有AZD9291甲磺酸盐毒性大、易潮解的问题，更适合用于药物开发。

USPTO Abstract

本发明公开了新的AZD9291药用盐，所述AZD9291的化学结构式如下：，所述药用盐为硫酸盐、对甲苯磺酸盐、酒石酸盐、醋酸盐或柠檬酸盐。本发明所提供的AZD9291药用盐具有与AZD9291甲磺酸盐相当或更高的溶解度，能满足生物利用度和药效要求，而且生物安全性更高，引湿性更低，克服了现有AZD9291甲磺酸盐毒性大、易潮解的问题，更适合用于药物开发。

Drugs covered by this patent

mobocertinib-succinate (MOBOCERTINIB SUCCINATE)

Patent Metadata

Patent number: CN106432231B
Jurisdiction: CN
Classification: —
Expires: 2018-06-12
Drug substance claim: No
Drug product claim: No
Assignee: Wuxi Baiaode Biological Science Co.,Ltd.
Source: FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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