CN Patent

CN106344521A — 一种高载药量可生物降解布比卡因微球的制备及其应用

Assigned to Shenyang Pharmaceutical University · Expires 2017-01-25 · 9y expired

What this patent protects

本发明涉及药物制剂技术领域，提供了一种高载药量布比卡因生物可降解微球的制备方法，以生物可降解的高分子量聚乳酸为载体材料，采用乳化溶剂挥发法，制备包载游离碱形式的布比卡因微球，经冻干后的布比卡因微球分散于注射用介质，局部注射给药，用于术后镇痛或缓解局部疼痛。所述布比卡因与载体材料的重量比为75:25~85:15,微球中布比卡因载药量可达到60%以上，可实现药物可在5~7天内释放完全。

USPTO Abstract

本发明涉及药物制剂技术领域，提供了一种高载药量布比卡因生物可降解微球的制备方法，以生物可降解的高分子量聚乳酸为载体材料，采用乳化溶剂挥发法，制备包载游离碱形式的布比卡因微球，经冻干后的布比卡因微球分散于注射用介质，局部注射给药，用于术后镇痛或缓解局部疼痛。所述布比卡因与载体材料的重量比为75:25~85:15,微球中布比卡因载药量可达到60%以上，可实现药物可在5~7天内释放完全。

Drugs covered by this patent

Bupivacaine Hydrochloride And Epinephrine (BUPIVACAINE) · Innocoll

Patent Metadata

Patent number: CN106344521A
Jurisdiction: CN
Classification: —
Expires: 2017-01-25
Drug substance claim: No
Drug product claim: No
Assignee: Shenyang Pharmaceutical University
Source: FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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