CN Patent

CN106316986B — 一种1-[2-(2,4-二甲基苯基硫烷基)苯基]哌嗪氢溴酸盐α型晶体的制备方法

Assigned to Sichuan Hongyuan Pharmaceutical Co.,Ltd. · Expires 2019-02-05 · 7y expired

What this patent protects

本发明提供了一种1‑[2‑(2,4‑二甲基苯基硫烷基)苯基]哌嗪氢溴酸盐α型晶体的制备方法，通过将1‑[2‑(2,4‑二甲基苯基硫烷基)苯基]哌嗪溶于反应溶剂后搅拌使其完全溶解，在40‑65℃下滴加氢溴酸，滴加完毕后搅拌均匀，40‑65℃下反应3‑65分钟后过滤，将滤饼干燥获得，该方法简单、稳定性好，合成收率和纯度高。

USPTO Abstract

本发明提供了一种1‑[2‑(2,4‑二甲基苯基硫烷基)苯基]哌嗪氢溴酸盐α型晶体的制备方法，通过将1‑[2‑(2,4‑二甲基苯基硫烷基)苯基]哌嗪溶于反应溶剂后搅拌使其完全溶解，在40‑65℃下滴加氢溴酸，滴加完毕后搅拌均匀，40‑65℃下反应3‑65分钟后过滤，将滤饼干燥获得，该方法简单、稳定性好，合成收率和纯度高。

Drugs covered by this patent

Patent Metadata

Patent number
CN106316986B
Jurisdiction
CN
Classification
—
Expires
2019-02-05
Drug substance claim
No
Drug product claim
No
Assignee
Sichuan Hongyuan Pharmaceutical Co.,Ltd.
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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