CN Patent

CN106176600A — 一种前列地尔冻干微乳剂、原料组合物及其制备方法

Assigned to Shanghai Advanced Pharmaceutical Engineering Research Center Ltd · Expires 2016-12-07 · 9y expired

What this patent protects

本发明公开了一种前列地尔冻干微乳剂、原料组合物及其制备方法，其原料组合物包括0.1～10mg/100mL的前列地尔、0.5～20g/100mL的油、0.5～30g/100mL的乳化剂、0.5～2g/100mL的助乳化剂、5～40mg/100mL的稳定剂、5～20g/100mL的冻干保护剂、0.5～500mg/100mL的pH调节剂和余量的水。其制备方法包括：在惰性氛围下制得油相和水相，将水相以0.5～5mL/min的滴加速度滴入油相中，于30～50℃下剪切乳化得到微乳；之后调节微乳pH至3.0～6.0，经无菌过滤，冷冻干燥即得。本发明的前列地尔冻干微乳剂…

USPTO Abstract

本发明公开了一种前列地尔冻干微乳剂、原料组合物及其制备方法，其原料组合物包括0.1～10mg/100mL的前列地尔、0.5～20g/100mL的油、0.5～30g/100mL的乳化剂、0.5～2g/100mL的助乳化剂、5～40mg/100mL的稳定剂、5～20g/100mL的冻干保护剂、0.5～500mg/100mL的pH调节剂和余量的水。其制备方法包括：在惰性氛围下制得油相和水相，将水相以0.5～5mL/min的滴加速度滴入油相中，于30～50℃下剪切乳化得到微乳；之后调节微乳pH至3.0～6.0，经无菌过滤，冷冻干燥即得。本发明的前列地尔冻干微乳剂粒径小、包封率高、稳定安全、高效靶向。

Drugs covered by this patent

Patent Metadata

Patent number
CN106176600A
Jurisdiction
CN
Classification
—
Expires
2016-12-07
Drug substance claim
No
Drug product claim
No
Assignee
Shanghai Advanced Pharmaceutical Engineering Research Center Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

Track this patent

Get a daily-checked alert when vulnerability score, expiry, classification, or assignee changes. Email, Slack, or Teams delivery. Pro: 50 watches, Free: 3.