CN Patent

CN105924381B — 一种哌马色林晶型c的制备方法

Assigned to Liangjiang Medicine Co Ltd · Expires 2019-04-16 · 7y expired

What this patent protects

本发明提供了一种哌马色林晶型C的制备方法，包括：将N‑(4‑氟苄基)‑N‑(1‑甲基哌啶‑4‑基)‑N＇‑(4‑(2‑甲基丙氧基)‑苯基甲基)脲的酒石酸盐的晶型A在丙酮中回流3～6小时，得到哌马色林晶型C。本发明创造性的通过简单的加热回流即可实现哌马色林晶型的转化，无需对溶剂进行脱氧处理，不需要惰性气体保护，也不需要添加晶种，操作步骤简单，无需苛刻条件，更利于产业化。

USPTO Abstract

本发明提供了一种哌马色林晶型C的制备方法，包括：将N‑(4‑氟苄基)‑N‑(1‑甲基哌啶‑4‑基)‑N＇‑(4‑(2‑甲基丙氧基)‑苯基甲基)脲的酒石酸盐的晶型A在丙酮中回流3～6小时，得到哌马色林晶型C。本发明创造性的通过简单的加热回流即可实现哌马色林晶型的转化，无需对溶剂进行脱氧处理，不需要惰性气体保护，也不需要添加晶种，操作步骤简单，无需苛刻条件，更利于产业化。

Drugs covered by this patent

Patent Metadata

Patent number
CN105924381B
Jurisdiction
CN
Classification
—
Expires
2019-04-16
Drug substance claim
No
Drug product claim
No
Assignee
Liangjiang Medicine Co Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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