CN Patent

CN105753910A — 一种卡格列净中间体的制备方法

Assigned to Kamp Pharmaceuticals Co Ltd · Expires 2016-07-13 · 10y expired

What this patent protects

本发明涉及一种卡格列净中间体：甲基1-C-(3-((5-(4-氟苯基)-2-噻吩基)甲基)-4-甲基苯基)-D-吡喃葡萄糖苷(I)的制备方法，包括以2-[(5-卤代-2-甲基苯基)甲基]-5-(4-氟苯基)噻吩(II)和2,3,4,6-四-O-三甲基硅基-D-葡萄糖酸内酯(III)为起始原料，和镁粉制成格式试剂，经过亲核取代、脱三甲基硅基制备得到，该制备方法较之前报道的方法安全、收率高、易控制。

USPTO Abstract

本发明涉及一种卡格列净中间体：甲基1-C-(3-((5-(4-氟苯基)-2-噻吩基)甲基)-4-甲基苯基)-D-吡喃葡萄糖苷(I)的制备方法，包括以2-[(5-卤代-2-甲基苯基)甲基]-5-(4-氟苯基)噻吩(II)和2,3,4,6-四-O-三甲基硅基-D-葡萄糖酸内酯(III)为起始原料，和镁粉制成格式试剂，经过亲核取代、脱三甲基硅基制备得到，该制备方法较之前报道的方法安全、收率高、易控制。

Drugs covered by this patent

Patent Metadata

Patent number
CN105753910A
Jurisdiction
CN
Classification
—
Expires
2016-07-13
Drug substance claim
No
Drug product claim
No
Assignee
Kamp Pharmaceuticals Co Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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