CN Patent

CN105566215B — 一种瑞戈非尼的制备方法

Assigned to Shenyang Pharmaceutical University · Expires 2018-02-16 · 8y expired

What this patent protects

本发明公开了一种瑞戈非尼的制备方法，其中引入新化合物4‑(3‑氟苯氧基)‑ N ‑甲基吡啶‑2‑甲酰胺（5）和4‑(3‑氟‑4‑氨基苯氧基)‑ N ‑甲基吡啶‑2‑甲酰胺（6）作为中间体，通过引入所述中间体提供一种具有反应条件温和、后处理简单、反应收率和纯度高、成本低和方法更合理的瑞戈非尼的制备方法。

USPTO Abstract

本发明公开了一种瑞戈非尼的制备方法，其中引入新化合物4‑(3‑氟苯氧基)‑ N ‑甲基吡啶‑2‑甲酰胺（5）和4‑(3‑氟‑4‑氨基苯氧基)‑ N ‑甲基吡啶‑2‑甲酰胺（6）作为中间体，通过引入所述中间体提供一种具有反应条件温和、后处理简单、反应收率和纯度高、成本低和方法更合理的瑞戈非尼的制备方法。

Drugs covered by this patent

Patent Metadata

Patent number
CN105566215B
Jurisdiction
CN
Classification
—
Expires
2018-02-16
Drug substance claim
No
Drug product claim
No
Assignee
Shenyang Pharmaceutical University
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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