CN Patent

CN105555771A — 无定形莱特莫韦及其用于口服施用的固体药物制剂

Assigned to Aic246 Lianghe Co · Expires 2016-05-04 · 10y expired

What this patent protects

本发明提供无定形莱特莫韦和其可口服施用的固体药物制剂(立即释放制剂)。所述无定形莱特莫韦当从有机溶液中分离出来时适合于立即释放制剂，所述无定形莱特莫韦的分离是通过在30℃至60℃的温度下将在挥发性有机溶剂、特别是丙酮中的有机溶液进行滚筒干燥，并且随后干燥所得的无定形莱特莫韦；或通过从选自丙酮或乙腈的水混溶性溶剂沉淀至作为反溶剂的过量水中来分离所述无定形莱特莫韦，并且随后过滤或浓缩所得无定形莱特莫韦。所述无定形莱特莫韦的立即释放制剂旨在用于与疱疹病毒群相关、优选地与巨细胞病毒(CMV)相关、甚至更优选地与人类巨细胞病毒(HCMV)相关的疾病的预防方法或治疗…

USPTO Abstract

本发明提供无定形莱特莫韦和其可口服施用的固体药物制剂(立即释放制剂)。所述无定形莱特莫韦当从有机溶液中分离出来时适合于立即释放制剂，所述无定形莱特莫韦的分离是通过在30℃至60℃的温度下将在挥发性有机溶剂、特别是丙酮中的有机溶液进行滚筒干燥，并且随后干燥所得的无定形莱特莫韦；或通过从选自丙酮或乙腈的水混溶性溶剂沉淀至作为反溶剂的过量水中来分离所述无定形莱特莫韦，并且随后过滤或浓缩所得无定形莱特莫韦。所述无定形莱特莫韦的立即释放制剂旨在用于与疱疹病毒群相关、优选地与巨细胞病毒(CMV)相关、甚至更优选地与人类巨细胞病毒(HCMV)相关的疾病的预防方法或治疗方法中。

Drugs covered by this patent

Patent Metadata

Patent number
CN105555771A
Jurisdiction
CN
Classification
—
Expires
2016-05-04
Drug substance claim
No
Drug product claim
No
Assignee
Aic246 Lianghe Co
Source
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