CN Patent

CN105481925B — 一种奥贝胆酸及其中间体的制备方法

Assigned to FUDAN ZHANGJIANG BIOLOGICAL MEDICINE Co Ltd SHANGHAI · Expires 2018-06-22 · 8y expired

What this patent protects

本发明涉及一种奥贝胆酸及其中间体的制备方法，3α‑羟基‑6α‑乙基‑7‑酮基‑5β‑胆烷酸，通过3α‑羟基‑6‑亚乙基‑7‑酮基‑5β‑胆烷酸苄酯之类化合物在催化剂和供氢体作用下反应得到；所述催化剂选自Pd/C、PtO 2 或兰尼镍，所述供氢体选自环己烯、环己二烯或者四氢化萘。本方法收率高、立体选择性高、安全性好、反应条件温和，适合于工业化生产。

USPTO Abstract

本发明涉及一种奥贝胆酸及其中间体的制备方法，3α‑羟基‑6α‑乙基‑7‑酮基‑5β‑胆烷酸，通过3α‑羟基‑6‑亚乙基‑7‑酮基‑5β‑胆烷酸苄酯之类化合物在催化剂和供氢体作用下反应得到；所述催化剂选自Pd/C、PtO 2 或兰尼镍，所述供氢体选自环己烯、环己二烯或者四氢化萘。本方法收率高、立体选择性高、安全性好、反应条件温和，适合于工业化生产。

Drugs covered by this patent

Patent Metadata

Patent number
CN105481925B
Jurisdiction
CN
Classification
—
Expires
2018-06-22
Drug substance claim
No
Drug product claim
No
Assignee
FUDAN ZHANGJIANG BIOLOGICAL MEDICINE Co Ltd SHANGHAI
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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