CN Patent

CN105461639B — 一种高纯度马西替坦的精制方法

Assigned to HEFEI JIUNUO MEDICAL TECHNOLOGY Co Ltd · Expires 2018-03-09 · 8y expired

What this patent protects

本发明公开了一种高纯度马西替坦的精制方法，是在避光条件下，将马西替坦粗品用新沸过的溶剂加热溶解，加入活性炭脱色5‑15min，趁热压滤，滤液避光降温至45‑55℃搅拌析晶1‑2h，再降温至20‑30℃搅拌析晶1‑2h，过滤，干燥，得马西替坦纯品。本方法具有操作简捷、收率高、产品纯等优点，收率85％以上，马西替坦纯品纯度在99.9％以上(HPLC检测)。

USPTO Abstract

本发明公开了一种高纯度马西替坦的精制方法，是在避光条件下，将马西替坦粗品用新沸过的溶剂加热溶解，加入活性炭脱色5‑15min，趁热压滤，滤液避光降温至45‑55℃搅拌析晶1‑2h，再降温至20‑30℃搅拌析晶1‑2h，过滤，干燥，得马西替坦纯品。本方法具有操作简捷、收率高、产品纯等优点，收率85％以上，马西替坦纯品纯度在99.9％以上(HPLC检测)。

Drugs covered by this patent

Patent Metadata

Patent number
CN105461639B
Jurisdiction
CN
Classification
—
Expires
2018-03-09
Drug substance claim
No
Drug product claim
No
Assignee
HEFEI JIUNUO MEDICAL TECHNOLOGY Co Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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