CN Patent

CN105326814A — 托吡酯缓释制剂药物组合物

Assigned to Beijing Wanquan Dezhong Medical Biological Technology Co Ltd · Expires 2016-02-17 · 10y expired

What this patent protects

本发明涉及药物缓释制剂药物组合物及其制备方法。所述的托吡酯缓释制剂由缓释颗粒加制剂辅料制备得到，缓释颗粒由35%-45%托吡酯、40%-50%填充剂、2.5%-6%粘合剂、2%-10%稳定剂、5.0%-6.5%缓释包衣材料、2.0%-3.0%致孔材料和1%-2%增塑剂组成。本发明中稳定剂的应用能显著提高制剂稳定性，减少药物降解。托吡酯缓释制剂服药后能维持平稳而有效的血药浓度，减少了副反应的发生率，很好的控制癫痫的发作。此外服药频率为一天一次，大大提高了患者顺应性。本发明采用流化床一步制粒，无需采用特殊工艺，易于工业生产。

USPTO Abstract

本发明涉及药物缓释制剂药物组合物及其制备方法。所述的托吡酯缓释制剂由缓释颗粒加制剂辅料制备得到，缓释颗粒由35%-45%托吡酯、40%-50%填充剂、2.5%-6%粘合剂、2%-10%稳定剂、5.0%-6.5%缓释包衣材料、2.0%-3.0%致孔材料和1%-2%增塑剂组成。本发明中稳定剂的应用能显著提高制剂稳定性，减少药物降解。托吡酯缓释制剂服药后能维持平稳而有效的血药浓度，减少了副反应的发生率，很好的控制癫痫的发作。此外服药频率为一天一次，大大提高了患者顺应性。本发明采用流化床一步制粒，无需采用特殊工艺，易于工业生产。

Drugs covered by this patent

Patent Metadata

Patent number
CN105326814A
Jurisdiction
CN
Classification
—
Expires
2016-02-17
Drug substance claim
No
Drug product claim
No
Assignee
Beijing Wanquan Dezhong Medical Biological Technology Co Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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