CN Patent

CN105272927A — 一种制备氯氮卓的新方法

Assigned to HUAZHONG PHARMACEUTICAL CO Ltd · Expires 2016-01-27 · 10y expired

What this patent protects

本发明公开一种制备氯氮卓的新方法，包括如下步骤：7-氯-5-苯基-1,3-二氢-2H-1,4-苯并二氮杂卓-2-酮-4-氧化物，在乙酸和无水硫酸镁存在下，与一甲胺的小分子脂肪醇溶液反应，制备氯氮卓。与现有的制备方法比较，本方法具有制备方法简便，反应条件温和，收率高；后处理过程简单，产物纯度高，环境污染小，适于工业化生产等优点。

USPTO Abstract

本发明公开一种制备氯氮卓的新方法，包括如下步骤：7-氯-5-苯基-1,3-二氢-2H-1,4-苯并二氮杂卓-2-酮-4-氧化物，在乙酸和无水硫酸镁存在下，与一甲胺的小分子脂肪醇溶液反应，制备氯氮卓。与现有的制备方法比较，本方法具有制备方法简便，反应条件温和，收率高；后处理过程简单，产物纯度高，环境污染小，适于工业化生产等优点。

Drugs covered by this patent

Patent Metadata

Patent number
CN105272927A
Jurisdiction
CN
Classification
—
Expires
2016-01-27
Drug substance claim
No
Drug product claim
No
Assignee
HUAZHONG PHARMACEUTICAL CO Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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