CN Patent

CN105153016B — 一种匹莫范色林的制备方法

Assigned to Beijing nukangda medicine Polytron Technologies Inc · Expires 2017-10-03 · 9y expired

What this patent protects

本发明公开了一种匹莫范色林的制备方法，该方法按照以下两个步骤依次进行：4‑异丁氧基苯甲胺与羰基二咪唑进行酰化反应得到N‑(4‑异丁氧基苯基)‑1H‑咪唑‑1‑甲酰胺，再与N‑(4‑氟苯基)‑1‑甲基哌啶‑4‑胺进行脲化反应得到匹莫范色林，本发明制备的匹莫范色林质量好，收率高，试剂毒性较小，操作简单易控，适合工业化生产。

USPTO Abstract

本发明公开了一种匹莫范色林的制备方法，该方法按照以下两个步骤依次进行：4‑异丁氧基苯甲胺与羰基二咪唑进行酰化反应得到N‑(4‑异丁氧基苯基)‑1H‑咪唑‑1‑甲酰胺，再与N‑(4‑氟苯基)‑1‑甲基哌啶‑4‑胺进行脲化反应得到匹莫范色林，本发明制备的匹莫范色林质量好，收率高，试剂毒性较小，操作简单易控，适合工业化生产。

Drugs covered by this patent

Patent Metadata

Patent number
CN105153016B
Jurisdiction
CN
Classification
—
Expires
2017-10-03
Drug substance claim
No
Drug product claim
No
Assignee
Beijing nukangda medicine Polytron Technologies Inc
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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