CN Patent

CN105153016A — 一种匹莫范色林的制备方法

Assigned to Beijing nukangda medicine Polytron Technologies Inc · Expires 2015-12-16 · 10y expired

What this patent protects

本发明公开了一种匹莫范色林的制备方法，该方法按照以下两个步骤依次进行：4-异丁氧基苯甲胺与羰基二咪唑进行酰化反应得到N-(4-异丁氧基苯基)-1H-咪唑-1-甲酰胺，再与N-(4-氟苯基)-1-甲基哌啶-4-胺进行脲化反应得到匹莫范色林，本发明制备的匹莫范色林质量好，收率高，试剂毒性较小，操作简单易控，适合工业化生产。

USPTO Abstract

本发明公开了一种匹莫范色林的制备方法，该方法按照以下两个步骤依次进行：4-异丁氧基苯甲胺与羰基二咪唑进行酰化反应得到N-(4-异丁氧基苯基)-1H-咪唑-1-甲酰胺，再与N-(4-氟苯基)-1-甲基哌啶-4-胺进行脲化反应得到匹莫范色林，本发明制备的匹莫范色林质量好，收率高，试剂毒性较小，操作简单易控，适合工业化生产。

Drugs covered by this patent

pimavanserin-tartrate (PIMAVANSERIN TARTRATE)

Patent Metadata

Patent number: CN105153016A
Jurisdiction: CN
Classification: —
Expires: 2015-12-16
Drug substance claim: No
Drug product claim: No
Assignee: Beijing nukangda medicine Polytron Technologies Inc
Source: FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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