CN Patent

CN105111167A — 一种沃替西汀半盐酸盐及其制备方法和药物组合物

Assigned to South China University of Technology SCUT · Expires 2015-12-02 · 10y expired

What this patent protects

本发明公开了一种沃替西汀半盐酸盐及其制备方法和药物组合物，沃替西汀半盐酸盐如I所示，该盐空间群为单斜晶系，两个沃替西汀分子共享一个质子，并通过N-H···Cl - 氢键与沃替西汀结合在一起构成基本结构单元。本发明所提供的沃替西汀半盐酸晶型稳定，结晶度高；制备方法操作简单，晶体中不含有溶剂。

USPTO Abstract

本发明公开了一种沃替西汀半盐酸盐及其制备方法和药物组合物，沃替西汀半盐酸盐如I所示，该盐空间群为单斜晶系，两个沃替西汀分子共享一个质子，并通过N-H···Cl - 氢键与沃替西汀结合在一起构成基本结构单元。本发明所提供的沃替西汀半盐酸晶型稳定，结晶度高；制备方法操作简单，晶体中不含有溶剂。

Drugs covered by this patent

vortioxetine-hydrobromide (VORTIOXETINE HYDROBROMIDE)

Patent Metadata

Patent number: CN105111167A
Jurisdiction: CN
Classification: —
Expires: 2015-12-02
Drug substance claim: No
Drug product claim: No
Assignee: South China University of Technology SCUT
Source: FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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