CN Patent

CN105017147B — 一种回收和利用Bedaquiline立体化学异构体的方法

Assigned to Institute of Materia Medica of CAMS and PUMC · Expires 2019-02-01 · 7y expired

What this patent protects

本发明涉及一种回收和再利用Bedaquiline立体化学异构体的方法，这些异构体包括(αR,βR),(αS,βS)和(αR,βS)‑6‑溴‑α‑[2‑(二甲基氨基)乙基]‑2‑甲氧基‑α‑1‑萘基‑β‑苯基‑3‑喹啉乙醇。回收的异构体可高转化率的生成X和Y，X和Y可再次用于Bedaquiline的合成，本工艺方法能够大大降低Bedaquiline的生产成本，提高原料的利用率。

USPTO Abstract

本发明涉及一种回收和再利用Bedaquiline立体化学异构体的方法，这些异构体包括(αR,βR),(αS,βS)和(αR,βS)‑6‑溴‑α‑[2‑(二甲基氨基)乙基]‑2‑甲氧基‑α‑1‑萘基‑β‑苯基‑3‑喹啉乙醇。回收的异构体可高转化率的生成X和Y，X和Y可再次用于Bedaquiline的合成，本工艺方法能够大大降低Bedaquiline的生产成本，提高原料的利用率。

Drugs covered by this patent

Patent Metadata

Patent number
CN105017147B
Jurisdiction
CN
Classification
—
Expires
2019-02-01
Drug substance claim
No
Drug product claim
No
Assignee
Institute of Materia Medica of CAMS and PUMC
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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