CN Patent

CN104987360A — 一类双烷氧酰胺烷基阳离子肽脂质及其合成方法和应用

Assigned to Dalian Minzu University · Expires 2015-10-21 · 11y expired

What this patent protects

一类双烷氧酰胺烷基阳离子肽脂质,其化学结构式为: 其分散在水中可以得到稳定性好、分散均匀,平均粒径在120nm左右,Zeta电位在30~50mV之间的阳离子肽脂质体。脂质体能有效压缩质粒DNA和siRNA,在体外体内都能高效转染,并对细胞和小鼠几乎不产生毒性。本发明所述的一类双烷氧酰胺烷基阳离子肽脂质作为基因载体可在基因转运中广泛应用。

USPTO Abstract

一类双烷氧酰胺烷基阳离子肽脂质,其化学结构式为: 其分散在水中可以得到稳定性好、分散均匀,平均粒径在120nm左右,Zeta电位在30~50mV之间的阳离子肽脂质体。脂质体能有效压缩质粒DNA和siRNA,在体外体内都能高效转染,并对细胞和小鼠几乎不产生毒性。本发明所述的一类双烷氧酰胺烷基阳离子肽脂质作为基因载体可在基因转运中广泛应用。

Drugs covered by this patent

Patent Metadata

Patent number
CN104987360A
Jurisdiction
CN
Classification
Expires
2015-10-21
Drug substance claim
No
Drug product claim
No
Assignee
Dalian Minzu University
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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