CN Patent

CN104945384A — 5-氯-6-[(2-亚氨基-1-吡咯烷)甲基]-2,4(1h,3h)-嘧啶二酮或其盐的制备方法

Assigned to Jiangsu Hansoh Pharmaceutical Group Co Ltd · Expires 2015-09-30 · 11y expired

What this patent protects

本发明提供一种5-氯-6-[(2-亚氨基-1-吡咯烷)甲基]-2,4(1H,3H)-嘧啶二酮或其盐的制备方法，以6-甲基嘧啶-2,4(1H,3H)-二酮为起始原料，通过6位甲基氧化，5位氢发生氯代，再还原6位醛基，与2-氨基吡咯烷或相应的盐缩合后得到目标产物。本发明操作简单，工艺稳定，适合工业化生产，且产率高，纯度高，成本低。

USPTO Abstract

本发明提供一种5-氯-6-[(2-亚氨基-1-吡咯烷)甲基]-2,4(1H,3H)-嘧啶二酮或其盐的制备方法，以6-甲基嘧啶-2,4(1H,3H)-二酮为起始原料，通过6位甲基氧化，5位氢发生氯代，再还原6位醛基，与2-氨基吡咯烷或相应的盐缩合后得到目标产物。本发明操作简单，工艺稳定，适合工业化生产，且产率高，纯度高，成本低。

Drugs covered by this patent

Patent Metadata

Patent number: CN104945384A
Jurisdiction: CN
Classification: —
Expires: 2015-09-30
Drug substance claim: No
Drug product claim: No
Assignee: Jiangsu Hansoh Pharmaceutical Group Co Ltd
Source: FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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