CN Patent

CN104888207B — 一种注射用比伐芦定的制备工艺

Assigned to HAINAN ZHONGHE PHARMACEUTICAL CO Ltd · Expires 2017-11-14 · 9y expired

What this patent protects

本发明属于药物制剂领域，具体涉及一种注射用比伐芦定的制备工艺。通过本发明的制备方法得到的比伐芦定具有纯度高、杂质少、稳定性好的特点。本发明所述的制备方法，包括以下步骤：(1)比伐卢定溶液配：将柠檬酸‐磷酸氢二钠缓冲溶液接入高速分散装置，加入比伐芦定原料药，搅拌溶解，加注射用水定容至100L，即可得到比伐卢定灌装溶液；(2)灌装；(3)冷冻干燥后得到注射用比伐卢定。

USPTO Abstract

本发明属于药物制剂领域，具体涉及一种注射用比伐芦定的制备工艺。通过本发明的制备方法得到的比伐芦定具有纯度高、杂质少、稳定性好的特点。本发明所述的制备方法，包括以下步骤：(1)比伐卢定溶液配：将柠檬酸‐磷酸氢二钠缓冲溶液接入高速分散装置，加入比伐芦定原料药，搅拌溶解，加注射用水定容至100L，即可得到比伐卢定灌装溶液；(2)灌装；(3)冷冻干燥后得到注射用比伐卢定。

Drugs covered by this patent

Patent Metadata

Patent number
CN104888207B
Jurisdiction
CN
Classification
—
Expires
2017-11-14
Drug substance claim
No
Drug product claim
No
Assignee
HAINAN ZHONGHE PHARMACEUTICAL CO Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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