CN Patent

CN104862308A — 一种用于指导他莫昔芬用药的试剂盒

Assigned to Beijing Auwiesen Gene Technology Co Ltd · Expires 2015-08-26 · 11y expired

What this patent protects

本发明公开了一种用于指导他莫昔芬用药的试剂盒。本发明保护一种引物组，由引物对甲和引物对乙组成；引物对甲由序列1所示的单链DNA分子和序列2所示的单链DNA分子组成；引物对乙由序列3所示的单链DNA分子和序列4所示的单链DNA分子组成。本发明还保护一种用于鉴定CYP2D6基因的100C>T点突变和CYP2D6基因的775delA突变的试剂盒，包括所述引物组。本发明提供的试剂盒可用于检测与他莫昔芬敏感性相关的两个SNP位点，进而可以用于临床指导他莫昔芬的个体化使用，提高临床治疗的针对性和可预见性。

USPTO Abstract

本发明公开了一种用于指导他莫昔芬用药的试剂盒。本发明保护一种引物组，由引物对甲和引物对乙组成；引物对甲由序列1所示的单链DNA分子和序列2所示的单链DNA分子组成；引物对乙由序列3所示的单链DNA分子和序列4所示的单链DNA分子组成。本发明还保护一种用于鉴定CYP2D6基因的100C>T点突变和CYP2D6基因的775delA突变的试剂盒，包括所述引物组。本发明提供的试剂盒可用于检测与他莫昔芬敏感性相关的两个SNP位点，进而可以用于临床指导他莫昔芬的个体化使用，提高临床治疗的针对性和可预见性。

Drugs covered by this patent

Patent Metadata

Patent number
CN104862308A
Jurisdiction
CN
Classification
—
Expires
2015-08-26
Drug substance claim
No
Drug product claim
No
Assignee
Beijing Auwiesen Gene Technology Co Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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