CN104725314A — 一种Ivacaftor的新晶型及其制备方法
Assigned to SHANGHAI HAOYUAN CHEMICAL TECHNOLOGY Co Ltd · Expires 2015-06-24 · 11y expired
What this patent protects
本发明公开了一种Ivacaftor的新晶型及其制备方法，属于医药化工技术领域。所述晶型的制备方法为：将Ivacaftor分散于结晶溶剂中，加热使固体溶解，缓慢冷却析晶，过滤，干燥，即得Ivacaftor的结晶。该新晶型粉末X-射线衍射图以2θ角表示在4.082±0.2°、6.135±0.2°、7.563±0.2°、8.374±0.2°、9.184±0.2°、11.705±0.2°、12.306±0.2°、17.858±0.2°、18.759±0.2°、20.92±0.2°处具有特征峰。本发明提供的Ivacaftor的新晶型纯度高、稳定性好，该晶型制备方法…
USPTO Abstract
本发明公开了一种Ivacaftor的新晶型及其制备方法，属于医药化工技术领域。所述晶型的制备方法为：将Ivacaftor分散于结晶溶剂中，加热使固体溶解，缓慢冷却析晶，过滤，干燥，即得Ivacaftor的结晶。该新晶型粉末X-射线衍射图以2θ角表示在4.082±0.2°、6.135±0.2°、7.563±0.2°、8.374±0.2°、9.184±0.2°、11.705±0.2°、12.306±0.2°、17.858±0.2°、18.759±0.2°、20.92±0.2°处具有特征峰。本发明提供的Ivacaftor的新晶型纯度高、稳定性好，该晶型制备方法工艺简单、产品收率高、环境友好。
Drugs covered by this patent
- Kalydeco (IVACAFTOR) · Vertex Pharms Inc
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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