CN Patent
CN104447923B — 2’‑脱氧‑2’‑氟‑2’‑甲基核苷衍生物及其制备方法与在制药中的用途
Assigned to China Pharmaceutical University · Expires 2018-03-30 · 8y expired
What this patent protects
本发明公开了2’‑脱氧‑2’‑氟‑2’‑甲基核苷衍生物及其制备方法与在制药中的用途。本发明式I化合物对野生型及S282T变异型HCV均具有较好的抑制效果,且细胞毒性低,因而可用于制备抗丙型肝炎病毒药物。本发明还提供了式I化合物的制备方法。
USPTO Abstract
本发明公开了2’‑脱氧‑2’‑氟‑2’‑甲基核苷衍生物及其制备方法与在制药中的用途。本发明式I化合物对野生型及S282T变异型HCV均具有较好的抑制效果,且细胞毒性低,因而可用于制备抗丙型肝炎病毒药物。本发明还提供了式I化合物的制备方法。
Drugs covered by this patent
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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