CN Patent

CN104402946B — 卡格列净中间体及其无定形的制备方法

Assigned to Jiangsu Hansoh Pharmaceutical Group Co Ltd · Expires 2018-01-02 · 8y expired

What this patent protects

本发明提供了卡格列净中间体及其无定形的制备方法，其中卡格列净无定形的制备方法的步骤包括通过将(1S)‑1,5‑脱氢‑1‑[3‑[[5‑(4‑氟苯基)‑2‑噻吩基]甲基]‑4‑甲基苯基]‑D‑葡萄糖醇在良性溶剂中加热溶清，然后滴加到快速搅拌的不良溶剂中，过滤析出的固体，得到无定形卡格列净。本发明的制备方法能够降低溶剂用量，所得产品易分离，而且，所得产品收率好、纯度高，方法操作简单。

USPTO Abstract

本发明提供了卡格列净中间体及其无定形的制备方法，其中卡格列净无定形的制备方法的步骤包括通过将(1S)‑1,5‑脱氢‑1‑[3‑[[5‑(4‑氟苯基)‑2‑噻吩基]甲基]‑4‑甲基苯基]‑D‑葡萄糖醇在良性溶剂中加热溶清，然后滴加到快速搅拌的不良溶剂中，过滤析出的固体，得到无定形卡格列净。本发明的制备方法能够降低溶剂用量，所得产品易分离，而且，所得产品收率好、纯度高，方法操作简单。

Drugs covered by this patent

Patent Metadata

Patent number
CN104402946B
Jurisdiction
CN
Classification
—
Expires
2018-01-02
Drug substance claim
No
Drug product claim
No
Assignee
Jiangsu Hansoh Pharmaceutical Group Co Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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