CN Patent

CN104276999A — 3-羟基-5-芳基吡啶-2-甲酰胺衍生物的制备方法及中间体

Assigned to China Pharmaceutical University · Expires 2015-01-14 · 11y expired

What this patent protects

本发明涉及药物合成领域。具体公开了具有慢性肾性贫血治疗作用的3-羟基-5-芳基吡啶-2-甲酰胺衍生物(I)的制备方法，其特征是本方法从5-溴-2-氰基-3-苄氧基吡啶出发，经过酰胺化反应、偶联反应、脱保护反应共3步反应制备得到化合物(I)。本发明方法合成步骤短，反应条件温和，成本较低，后处理方便，适合于规模化生产。

USPTO Abstract

本发明涉及药物合成领域。具体公开了具有慢性肾性贫血治疗作用的3-羟基-5-芳基吡啶-2-甲酰胺衍生物(I)的制备方法，其特征是本方法从5-溴-2-氰基-3-苄氧基吡啶出发，经过酰胺化反应、偶联反应、脱保护反应共3步反应制备得到化合物(I)。本发明方法合成步骤短，反应条件温和，成本较低，后处理方便，适合于规模化生产。

Drugs covered by this patent

Patent Metadata

Patent number
CN104276999A
Jurisdiction
CN
Classification
—
Expires
2015-01-14
Drug substance claim
No
Drug product claim
No
Assignee
China Pharmaceutical University
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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