CN Patent

CN103760286A — 一种用高效液相色谱法测定琥珀酸索非那新中间体光学纯度的方法

Assigned to Beijing Wanquan Dezhong Medical Biological Technology Co Ltd · Expires 2014-04-30 · 12y expired

What this patent protects

本发明属分析化学领域，涉及了一种用液相色谱法分离琥珀酸索非那新中间体(S)-1-苯基-1,2,3,4-四氢异喹啉消旋体的方法，该方法采用以纤维素-三[3,5-二甲苯基氨基甲酸酯]为填料的手性色谱柱，以正己烷-低级醇溶液为流动相，可以定量测定琥珀酸索非那新中间体光学异构体的含量，指示琥珀酸索非那新中间体光学异构体的稳定性。本发明方法专属性强，准确度高，操作简便。

USPTO Abstract

本发明属分析化学领域，涉及了一种用液相色谱法分离琥珀酸索非那新中间体(S)-1-苯基-1,2,3,4-四氢异喹啉消旋体的方法，该方法采用以纤维素-三[3,5-二甲苯基氨基甲酸酯]为填料的手性色谱柱，以正己烷-低级醇溶液为流动相，可以定量测定琥珀酸索非那新中间体光学异构体的含量，指示琥珀酸索非那新中间体光学异构体的稳定性。本发明方法专属性强，准确度高，操作简便。

Drugs covered by this patent

Patent Metadata

Patent number
CN103760286A
Jurisdiction
CN
Classification
—
Expires
2014-04-30
Drug substance claim
No
Drug product claim
No
Assignee
Beijing Wanquan Dezhong Medical Biological Technology Co Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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