CN Patent

CN103751140A — 一种Cabozantinib分散片及其制备方法

Assigned to Qingdao Tumour Hospital · Expires 2014-04-30 · 12y expired

What this patent protects

本发明公开了一种Cabozantinib分散片及其制备方法和应用。本发明所述的Cabozantinib分散片由如下按照重量百分数计的组分组成：Cabozantinib10～60%，填充剂10～40%，崩解剂10～50%，酸化剂10～50%，粘合剂0.1～10%，润滑剂及助流剂0.1～20%。本发明所述分散片与普通片比较，本发明所述的Cabozantinib分散片中不含表面活性剂，其溶解性、分散性和崩解性亦良好，可在1分钟内即可崩解完全。采用本发明方法制备的Cabozantinib分散片，溶出度高，生物利用度好，体内分布迅速，质量稳定，口感好，其制备方法简…

USPTO Abstract

本发明公开了一种Cabozantinib分散片及其制备方法和应用。本发明所述的Cabozantinib分散片由如下按照重量百分数计的组分组成：Cabozantinib10～60%，填充剂10～40%，崩解剂10～50%，酸化剂10～50%，粘合剂0.1～10%，润滑剂及助流剂0.1～20%。本发明所述分散片与普通片比较，本发明所述的Cabozantinib分散片中不含表面活性剂，其溶解性、分散性和崩解性亦良好，可在1分钟内即可崩解完全。采用本发明方法制备的Cabozantinib分散片，溶出度高，生物利用度好，体内分布迅速，质量稳定，口感好，其制备方法简单易行，适用于工业生产。

Drugs covered by this patent

cabozantinib-s-malate (CABOZANTINIB S-MALATE)

Patent Metadata

Patent number: CN103751140A
Jurisdiction: CN
Classification: —
Expires: 2014-04-30
Drug substance claim: No
Drug product claim: No
Assignee: Qingdao Tumour Hospital
Source: FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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