CN Patent

CN103588767B — 达拉菲尼的制备方法

Assigned to Beijing Hengtong innovation integrated housing assembly Co., Ltd · Expires 2016-01-20 · 10y expired

What this patent protects

本发明揭示了一种达拉菲尼(Dabrafenib)的制备方法，其包括如下步骤：以3-(3-氨基-2-氟苯基)-3-氧杂-丙酸酯(II)为原料，经过磺酰胺化、卤代、噻唑环合、酰化和嘧啶环合等步骤制得达拉菲尼(I)。该制备方法原料易得、工艺简洁、条件温和，适应工业化生产，促进该原料药的经济技术发展。

USPTO Abstract

本发明揭示了一种达拉菲尼(Dabrafenib)的制备方法，其包括如下步骤：以3-(3-氨基-2-氟苯基)-3-氧杂-丙酸酯(II)为原料，经过磺酰胺化、卤代、噻唑环合、酰化和嘧啶环合等步骤制得达拉菲尼(I)。该制备方法原料易得、工艺简洁、条件温和，适应工业化生产，促进该原料药的经济技术发展。

Drugs covered by this patent

Patent Metadata

Patent number
CN103588767B
Jurisdiction
CN
Classification
—
Expires
2016-01-20
Drug substance claim
No
Drug product claim
No
Assignee
Beijing Hengtong innovation integrated housing assembly Co., Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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