CN Patent

CN103387509B — 一种hcv蛋白酶抑制剂中间体的制备方法

Assigned to CHONGQING PORTON FINE CHEMICALS Co Ltd · Expires 2016-06-08 · 10y expired

What this patent protects

本发明提供一种HCV蛋白酶抑制剂TMC435的中间体双环内酯酰胺(I)的制备方法，即以一种辛可尼丁盐(IV)为原料与氯甲酸酯类化合物形成混酐(III)，再将混酐同N-甲基己烯胺(NMHA)(II)进行缩合，从而得到目标产物双环内酯酰胺化合物(I)。 <!--1-->

USPTO Abstract

本发明提供一种HCV蛋白酶抑制剂TMC435的中间体双环内酯酰胺(I)的制备方法，即以一种辛可尼丁盐(IV)为原料与氯甲酸酯类化合物形成混酐(III)，再将混酐同N-甲基己烯胺(NMHA)(II)进行缩合，从而得到目标产物双环内酯酰胺化合物(I)。 <!--1-->

Drugs covered by this patent

Patent Metadata

Patent number
CN103387509B
Jurisdiction
CN
Classification
—
Expires
2016-06-08
Drug substance claim
No
Drug product claim
No
Assignee
CHONGQING PORTON FINE CHEMICALS Co Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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