CN Patent

CN103113378B — 一种盐酸羟吗啡酮的合成方法

Assigned to BEIJING HWELLS PHARMACEUTICAL Co Ltd · Expires 2016-04-06 · 10y expired

What this patent protects

本发明公开了一种盐酸羟吗啡酮的合成方法，主要有以下步骤：1）以盐酸羟考酮为起始原料，碱化成游离碱；2）进行脱甲基反应得到羟吗啡酮；3）羟吗啡酮在酸性条件下进行氢化反应；4）氢化后的产品与盐酸成盐得到目标产物盐酸羟吗啡酮。本发明的合成方法，原料价廉易得，产品纯度好，操作简便，适合工业化生产。

USPTO Abstract

本发明公开了一种盐酸羟吗啡酮的合成方法，主要有以下步骤：1）以盐酸羟考酮为起始原料，碱化成游离碱；2）进行脱甲基反应得到羟吗啡酮；3）羟吗啡酮在酸性条件下进行氢化反应；4）氢化后的产品与盐酸成盐得到目标产物盐酸羟吗啡酮。本发明的合成方法，原料价廉易得，产品纯度好，操作简便，适合工业化生产。

Drugs covered by this patent

oxymorphone-hydrochloride (OXYMORPHONE HYDROCHLORIDE)

Patent Metadata

Patent number: CN103113378B
Jurisdiction: CN
Classification: —
Expires: 2016-04-06
Drug substance claim: No
Drug product claim: No
Assignee: BEIJING HWELLS PHARMACEUTICAL Co Ltd
Source: FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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