CN Patent

CN102731510B — 替卡格雷的衍生物、制备方法及其药物用途

Assigned to Borui Pharmaceutical (suzhou) Ltd By Share Ltd · Expires 2015-12-16 · 10y expired

What this patent protects

本发明提供了下式所示的替卡格雷衍生物或其药物上可接受的盐，其中<b>R 1 </b><b>、</b><b>R 2 </b><b>、</b><b>R 3 </b>可以选自氨基酸残基或乙酰水杨酰基；以及制备这些替卡格雷衍生物或其药物上可接受的盐的方法；本发明还提供了上述的替卡格雷衍生物或其药物上可接受的盐在制备用于治疗凝血相关性疾病的药物中的应用，上述的衍生物可以提高替卡格雷的生物利用度或者增强替卡格雷与阿司匹林的联合用药的效果。

USPTO Abstract

本发明提供了下式所示的替卡格雷衍生物或其药物上可接受的盐，其中<b>R 1 </b><b>、</b><b>R 2 </b><b>、</b><b>R 3 </b>可以选自氨基酸残基或乙酰水杨酰基；以及制备这些替卡格雷衍生物或其药物上可接受的盐的方法；本发明还提供了上述的替卡格雷衍生物或其药物上可接受的盐在制备用于治疗凝血相关性疾病的药物中的应用，上述的衍生物可以提高替卡格雷的生物利用度或者增强替卡格雷与阿司匹林的联合用药的效果。

Drugs covered by this patent

Patent Metadata

Patent number
CN102731510B
Jurisdiction
CN
Classification
—
Expires
2015-12-16
Drug substance claim
No
Drug product claim
No
Assignee
Borui Pharmaceutical (suzhou) Ltd By Share Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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