CN Patent

CN102688185A — 一种稳定的帕洛诺司琼注射液及其制备方法

Assigned to QILU PHARMACEUTICAL (HAINAN) CO Ltd · Expires 2012-09-26 · 14y expired

What this patent protects

本发明提供一种稳定的帕洛诺司琼注射液及其制备方法，该帕洛诺司琼注射液含有主药帕洛诺司琼或其药学上可接受的盐以及pH缓冲剂、pH调节剂和注射用水。所述的pH缓冲剂选自醋酸、醋酸钠或醋酸铵之一或组合，所述的pH调节剂为氢氧化钠或盐酸。本发明的帕洛诺司琼注射液在灭菌过程中药液pH随温度和时间变化而无明显波动，主要活性成分没有明显降解，灭菌后样品的稳定性好。

USPTO Abstract

本发明提供一种稳定的帕洛诺司琼注射液及其制备方法，该帕洛诺司琼注射液含有主药帕洛诺司琼或其药学上可接受的盐以及pH缓冲剂、pH调节剂和注射用水。所述的pH缓冲剂选自醋酸、醋酸钠或醋酸铵之一或组合，所述的pH调节剂为氢氧化钠或盐酸。本发明的帕洛诺司琼注射液在灭菌过程中药液pH随温度和时间变化而无明显波动，主要活性成分没有明显降解，灭菌后样品的稳定性好。

Drugs covered by this patent

Clinimix E 2.75/5 Sulfite Free W/ Elect In Dextrose 5% W/ Calcium In Plastic Container (POTASSIUM PHOSPHATE, DIBASIC) · Pfizer

Patent Metadata

Patent number: CN102688185A
Jurisdiction: CN
Classification: —
Expires: 2012-09-26
Drug substance claim: No
Drug product claim: No
Assignee: QILU PHARMACEUTICAL (HAINAN) CO Ltd
Source: FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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