CN Patent

CN102627663A — 含氟吡啶硼酸的制备方法

Assigned to Shanghai Taitan Chemical Co Ltd · Expires 2012-08-08 · 14y expired

What this patent protects

本发明医药中间体的合成，公开了一种含氟吡啶硼酸的制备方法，将含氟溴取代吡啶和三烷基硼酸酯混合后，在氮气或者惰性气体保护下滴加烷基锂，含氟溴取代吡啶在低温下与烷基锂反应含氟吡啶锂盐，然后与三烷基硼酸酯反应，经稀酸或稀碱水解并萃取后得到相应的含氟吡啶硼酸。本方法可以用于合成多种含氟吡啶硼酸，收率高，具有广阔市场前景。

USPTO Abstract

本发明医药中间体的合成，公开了一种含氟吡啶硼酸的制备方法，将含氟溴取代吡啶和三烷基硼酸酯混合后，在氮气或者惰性气体保护下滴加烷基锂，含氟溴取代吡啶在低温下与烷基锂反应含氟吡啶锂盐，然后与三烷基硼酸酯反应，经稀酸或稀碱水解并萃取后得到相应的含氟吡啶硼酸。本方法可以用于合成多种含氟吡啶硼酸，收率高，具有广阔市场前景。

Drugs covered by this patent

Patent Metadata

Patent number
CN102627663A
Jurisdiction
CN
Classification
—
Expires
2012-08-08
Drug substance claim
No
Drug product claim
No
Assignee
Shanghai Taitan Chemical Co Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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