CN Patent

CN102414196A — 改进的方法

Assigned to Generics UK Ltd · Expires 2012-04-11 · 14y expired

What this patent protects

本发明涉及用于制备3-(4-氨基-1-氧代-1，3-二氢-异吲哚-2-基)-哌啶-2，6-二酮(I)(来那度胺)和它的中间体3-(1-氧代-4-硝基-1，3-二氢-异吲哚-2-基)-哌啶-2，6-二酮的改进方法。本发明还涉及用于制备用作活性药物成分或用作制备来那度胺的另外的晶形或非晶形的中间体的来那度胺晶形A的改进方法、包含来那度胺晶形A的组合物和它们在治疗疾病中的应用。

USPTO Abstract

本发明涉及用于制备3-(4-氨基-1-氧代-1，3-二氢-异吲哚-2-基)-哌啶-2，6-二酮(I)(来那度胺)和它的中间体3-(1-氧代-4-硝基-1，3-二氢-异吲哚-2-基)-哌啶-2，6-二酮的改进方法。本发明还涉及用于制备用作活性药物成分或用作制备来那度胺的另外的晶形或非晶形的中间体的来那度胺晶形A的改进方法、包含来那度胺晶形A的组合物和它们在治疗疾病中的应用。

Drugs covered by this patent

Patent Metadata

Patent number
CN102414196A
Jurisdiction
CN
Classification
—
Expires
2012-04-11
Drug substance claim
No
Drug product claim
No
Assignee
Generics UK Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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