CN Patent

CN102369189B — 氟喹诺酮羧酸分子晶体

Assigned to Bausch and Lomb Inc · Expires 2014-12-31 · 11y expired

What this patent protects

(R)-(+)-7-(3-氨基-2，3，4，5，6，7-六氢-1H-氮杂 -1-基)-8-氯-1-环丙基-6-氟-1，4-二氢-4-氧代喹啉-3-羧酸的分子晶形，其特征在于以下特征中的至少一种：(a)X-射线粉末衍射(“XRPD”)光谱包含在2θ角10.6、15、19.7、21.1和22°±0.2°的峰；(b)DSC熔融峰在288℃；(c) 13 C NMR光谱具有在23.3、27.7、41.1、54.5、116.6和153.5ppm的峰；以及(d)pKa值为5.65和9.91。

USPTO Abstract

(R)-(+)-7-(3-氨基-2，3，4，5，6，7-六氢-1H-氮杂 -1-基)-8-氯-1-环丙基-6-氟-1，4-二氢-4-氧代喹啉-3-羧酸的分子晶形，其特征在于以下特征中的至少一种：(a)X-射线粉末衍射(“XRPD”)光谱包含在2θ角10.6、15、19.7、21.1和22°±0.2°的峰；(b)DSC熔融峰在288℃；(c) 13 C NMR光谱具有在23.3、27.7、41.1、54.5、116.6和153.5ppm的峰；以及(d)pKa值为5.65和9.91。

Drugs covered by this patent

besifloxacin-hydrochloride (BESIFLOXACIN HYDROCHLORIDE)

Patent Metadata

Patent number: CN102369189B
Jurisdiction: CN
Classification: —
Expires: 2014-12-31
Drug substance claim: No
Drug product claim: No
Assignee: Bausch and Lomb Inc
Source: FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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