CN Patent

CN102276606A — 8-[{1-(3,5-双-(三氟甲基)苯基)-乙氧基}-甲基]-8-苯基-1,7-二氮杂-螺[4.5]癸-2-酮的甲苯磺酸盐及其制备方法

Assigned to Merck Sharp and Dohme LLC · Expires 2011-12-14 · 14y expired

What this patent protects

本申请涉及8-[{1-(3，5-双-(三氟甲基)苯基)-乙氧基}-甲基]-8-苯基-1，7-二氮杂-螺[4.5]癸-2-酮的甲苯磺酸盐及其制备方法。本申请公开了由式I表示的(5S，8S)-8-[{(1R)-1-(3，5-双-(三氟甲基)苯基)-乙氧基}-甲基]-8-苯基-1，7-二氮杂螺[4.5]癸-2-酮的盐酸盐及甲苯磺酸盐结晶盐形式及其制备方法。

USPTO Abstract

本申请涉及8-[{1-(3，5-双-(三氟甲基)苯基)-乙氧基}-甲基]-8-苯基-1，7-二氮杂-螺[4.5]癸-2-酮的甲苯磺酸盐及其制备方法。本申请公开了由式I表示的(5S，8S)-8-[{(1R)-1-(3，5-双-(三氟甲基)苯基)-乙氧基}-甲基]-8-苯基-1，7-二氮杂螺[4.5]癸-2-酮的盐酸盐及甲苯磺酸盐结晶盐形式及其制备方法。

Drugs covered by this patent

rolapitant-hydrochloride (ROLAPITANT HYDROCHLORIDE)

Patent Metadata

Patent number: CN102276606A
Jurisdiction: CN
Classification: —
Expires: 2011-12-14
Drug substance claim: No
Drug product claim: No
Assignee: Merck Sharp and Dohme LLC
Source: FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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