CN Patent

CN102238945B — 药物制剂514

Assigned to Kudos Pharmaceuticals Ltd · Expires 2014-10-29 · 12y expired

What this patent protects

本发明涉及一种药物制剂，其在含表现出低吸湿性和高软化温度的基质聚合物的固体分散体中包含药物4-[3-(4-环丙烷羰基-哌嗪-1-羰基)-4-氟-苄基]-2H-酞嗪-1-酮，所述基质聚合物为如共聚维酮。本发明还涉及由这种制剂提供的药物的每日药物剂型。此外，本发明涉及表现出低吸湿性和高软化温度的基质聚合物在含4-[3-(4-环丙烷羰基-哌嗪-1-羰基)-4-氟-苄基]-2H-酞嗪-1-酮的固体分散体中用于提高该药物的生物利用率的用途。

USPTO Abstract

本发明涉及一种药物制剂，其在含表现出低吸湿性和高软化温度的基质聚合物的固体分散体中包含药物4-[3-(4-环丙烷羰基-哌嗪-1-羰基)-4-氟-苄基]-2H-酞嗪-1-酮，所述基质聚合物为如共聚维酮。本发明还涉及由这种制剂提供的药物的每日药物剂型。此外，本发明涉及表现出低吸湿性和高软化温度的基质聚合物在含4-[3-(4-环丙烷羰基-哌嗪-1-羰基)-4-氟-苄基]-2H-酞嗪-1-酮的固体分散体中用于提高该药物的生物利用率的用途。

Drugs covered by this patent

afatinib-dimaleate (AFATINIB DIMALEATE)

Patent Metadata

Patent number: CN102238945B
Jurisdiction: CN
Classification: —
Expires: 2014-10-29
Drug substance claim: No
Drug product claim: No
Assignee: Kudos Pharmaceuticals Ltd
Source: FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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