CN Patent

CN102210872A — 一种聚乙二醇修饰肽药物制剂及其制备方法

Assigned to Hybio Pharmaceutical Co Ltd · Expires 2011-10-12 · 15y expired

What this patent protects

本发明提供一种稳定的聚乙二醇修饰肽药物制剂及其制备方法。药物制剂包含聚乙二醇修饰肽和缓冲剂,制剂的pH为4.0-7.0，所述的缓冲剂为醋酸盐缓冲液、枸橼酸盐缓冲液、磷酸盐缓冲液、酒石酸盐缓冲液中的一种或其任意两种或两种以上的组合。其包括下述步骤：称取处方量缓冲剂，用注射用水溶解并移入配液罐；用上述溶液将处方量的聚乙二醇修饰肽溶解，并稀释至处方浓度；用滤膜过滤除菌，得聚乙二醇修饰肽注射液。本发明的制剂长期稳定性明显提高。

USPTO Abstract

本发明提供一种稳定的聚乙二醇修饰肽药物制剂及其制备方法。药物制剂包含聚乙二醇修饰肽和缓冲剂,制剂的pH为4.0-7.0，所述的缓冲剂为醋酸盐缓冲液、枸橼酸盐缓冲液、磷酸盐缓冲液、酒石酸盐缓冲液中的一种或其任意两种或两种以上的组合。其包括下述步骤：称取处方量缓冲剂，用注射用水溶解并移入配液罐；用上述溶液将处方量的聚乙二醇修饰肽溶解，并稀释至处方浓度；用滤膜过滤除菌，得聚乙二醇修饰肽注射液。本发明的制剂长期稳定性明显提高。

Drugs covered by this patent

Patent Metadata

Patent number
CN102210872A
Jurisdiction
CN
Classification
—
Expires
2011-10-12
Drug substance claim
No
Drug product claim
No
Assignee
Hybio Pharmaceutical Co Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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