CN Patent

CN101987081B — 一种控释制剂

Assigned to Individual · Expires 2012-08-08 · 14y expired

What this patent protects

本发明揭示了一种性能改善的控释制剂。该控释制剂包括：含有药物的核芯及外覆于上述核芯的几乎不溶于水及胃和肠消化液的控释衣膜，上述控释衣膜含有被可溶于胃和/或肠消化液的但几乎不溶于水的聚合物衣膜包覆的可溶于水的药用添加剂的颗粒物，该聚合物与该药用添加剂不能发生化学反应或者能发生化学反应但不生成不溶于水的非气态的产物及药学上不可接受的产物，且该聚合物的量不超过该药用添加剂的量的700％。本发明还揭示了该控释制的制备方法。该控释制剂具有下列优势：药物释放重现性被提高；释药时滞被降低，释药放加快，生物利用度被提高；可以实现药物在胃肠道中定位控释释放、延时控释释放、…

USPTO Abstract

本发明揭示了一种性能改善的控释制剂。该控释制剂包括：含有药物的核芯及外覆于上述核芯的几乎不溶于水及胃和肠消化液的控释衣膜，上述控释衣膜含有被可溶于胃和/或肠消化液的但几乎不溶于水的聚合物衣膜包覆的可溶于水的药用添加剂的颗粒物，该聚合物与该药用添加剂不能发生化学反应或者能发生化学反应但不生成不溶于水的非气态的产物及药学上不可接受的产物，且该聚合物的量不超过该药用添加剂的量的700％。本发明还揭示了该控释制的制备方法。该控释制剂具有下列优势：药物释放重现性被提高；释药时滞被降低，释药放加快，生物利用度被提高；可以实现药物在胃肠道中定位控释释放、延时控释释放、间隙式或脉冲式控释释放；等等。

Drugs covered by this patent

Patent Metadata

Patent number
CN101987081B
Jurisdiction
CN
Classification
—
Expires
2012-08-08
Drug substance claim
No
Drug product claim
No
Assignee
Individual
Source
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