CN Patent

CN101415686A — 作为聚(adp-核糖)聚合酶(parp)抑制剂的酰胺取代的吲唑和苯并三唑衍生物

Assigned to MSD Italia SRL · Expires 2009-04-22 · 17y expired

What this patent protects

本发明涉及式I化合物及其药学上可接受的盐或互变异构体，所述化合物为聚(ADP－核糖)聚合酶(PARP)的抑制剂，且因此用于治疗癌症、炎症性疾病、再灌注损伤、局部缺血性病症、中风、肾衰竭、心血管疾病、非心血管疾病的血管疾病、糖尿病、神经变性疾病、逆转录病毒感染、视网膜损伤或皮肤衰老和UV－引起的皮肤损伤，且用作癌症治疗的化学增敏剂或放射增敏剂。

USPTO Abstract

本发明涉及式I化合物及其药学上可接受的盐或互变异构体，所述化合物为聚(ADP－核糖)聚合酶(PARP)的抑制剂，且因此用于治疗癌症、炎症性疾病、再灌注损伤、局部缺血性病症、中风、肾衰竭、心血管疾病、非心血管疾病的血管疾病、糖尿病、神经变性疾病、逆转录病毒感染、视网膜损伤或皮肤衰老和UV－引起的皮肤损伤，且用作癌症治疗的化学增敏剂或放射增敏剂。

Drugs covered by this patent

Patent Metadata

Patent number: CN101415686A
Jurisdiction: CN
Classification: —
Expires: 2009-04-22
Drug substance claim: No
Drug product claim: No
Assignee: MSD Italia SRL
Source: FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

Track this patent

Get a daily-checked alert when vulnerability score, expiry, classification, or assignee changes. Email, Slack, or Teams delivery. Pro: 50 watches, Free: 3.