CN Patent

CN100348180C — 盐酸曲马多口腔崩解片剂及其制备方法

Assigned to Henan Handsome Pharmaceutical Co Ltd · Expires 2007-11-14 · 19y expired

What this patent protects

一种盐酸曲马多口腔崩解片剂及其制备方法，主要是将盐酸曲马多和固体分散载体预先制得固体分散体，然后再与辅料填充剂、崩解剂、矫味剂、润滑剂均匀混合，采用直接压片法、干法制粒压片法或湿法制粒压片法，即得。它不仅制备工艺简单，而且可以克服已有盐酸曲马多口服制剂吸收起效慢及对老人，儿童或吞咽困难的患者服用困难的缺陷。同时，适合于急诊患者，也方便野外作业、旅游等无水情况下服用。将本发明片剂置于口腔中，遇唾液会迅速崩解，并通过口腔粘膜迅速吸收，起效。它不仅服用方便，而对适应症起效快，达峰早，疗效明显。

USPTO Abstract

一种盐酸曲马多口腔崩解片剂及其制备方法，主要是将盐酸曲马多和固体分散载体预先制得固体分散体，然后再与辅料填充剂、崩解剂、矫味剂、润滑剂均匀混合，采用直接压片法、干法制粒压片法或湿法制粒压片法，即得。它不仅制备工艺简单，而且可以克服已有盐酸曲马多口服制剂吸收起效慢及对老人，儿童或吞咽困难的患者服用困难的缺陷。同时，适合于急诊患者，也方便野外作业、旅游等无水情况下服用。将本发明片剂置于口腔中，遇唾液会迅速崩解，并通过口腔粘膜迅速吸收，起效。它不仅服用方便，而对适应症起效快，达峰早，疗效明显。

Drugs covered by this patent

Patent Metadata

Patent number: CN100348180C
Jurisdiction: CN
Classification: —
Expires: 2007-11-14
Drug substance claim: No
Drug product claim: No
Assignee: Henan Handsome Pharmaceutical Co Ltd
Source: FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

Track this patent

Get a daily-checked alert when vulnerability score, expiry, classification, or assignee changes. Email, Slack, or Teams delivery. Pro: 50 watches, Free: 3.