CA3254279A1 — Dosage forms and use thereof

USPTO Abstract

A method for 3D printing an oral drug dosage form comprises providing a homogenous melted mixture of an API and a first erodible material, a melted substrate, and a melted second erodible material; extruding the homogenous melted mixture through a printing nozzle; depositing the extruded mixture on a planar surface; separately extruding the melted substrate and the melted second erodible material through the printing nozzle; separately depositing the extruded melted substrate and the extruded melted second erodible material on the planar surface, thereby obtaining the oral dosage form. The dosage form comprises a water insoluble substrate forming a compartment and a drug content contained within the compartment. The drug content comprises the first erodible material admixed with the API. The compartment is sealed by a plug comprising die second erodible material not admixed with the API.