CA3225293A1 — Solid state forms
Assigned to Amgen Inc · Expires 2020-11-26 · 5y expired
What this patent protects
The present disclosure provides crystalline and amorphous forms of 6-fluoro-7-(2-fluoro-6-hydroxypheny1)-1-(4-methy1-2-(2-propany1)-3-pyridiny1)-4-((2S)-2-methyl-4-(2-propenoy1)-1-piperazinyl)pyrido[2,3-dlpyrimidin-2(1H)-one, including several anhydrous,hydrate and solvate forms,…
USPTO Abstract
The present disclosure provides crystalline and amorphous forms of 6-fluoro-7-(2-fluoro-6-hydroxypheny1)-1-(4-methy1-2-(2-propany1)-3-pyridiny1)-4-((2S)-2-methyl-4-(2-propenoy1)-1-piperazinyl)pyrido[2,3-dlpyrimidin-2(1H)-one, including several anhydrous,hydrate and solvate forms, and solid state forms thereof, pharmaceutical compositions, and methods of treating a disease mediated by KRAS G12C inhibition.
Drugs covered by this patent
- Lumakras (SOTORASIB) · Amgen
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
Track this patent
Get a daily-checked alert when vulnerability score, expiry, classification, or assignee changes. Email, Slack, or Teams delivery. Pro: 50 watches, Free: 3.