CA3213864A1 — Dosing regimen of tradipitant

USPTO Abstract

ABSTRACT Disclosed herein are uses of tradipitant for the treatment of a patient afflicted with a disease or disorder ameliorated by tradipitant, and tradipitant for use in the treatment of a disease or disorder ameliorated by tradipitant, and for use in the preparation of a medicament for the treatment of a disease or disorder ameliorated by tradipitant. Such diseases and disorders ameliorated by tradipitant include, for example, pruritus, atopic dermatitis, pain, a behavioral stressor, craving, nausea, vomiting, substance dependence, anxiety, and diseases and disorders caused by an over-expression of substance P or over-stimulation of the neurokinin-1 (NK-1) receptor. In the uses disclosed herein, the tradipitant is in a solid immediate release form for oral administration comprising tradipitant and one or more pharmaceutically acceptable excipients, at a dose of 85 mg/day of tradipitant. Date Recue/Date Received 2023-09-25